in 2021 (Figure 1) 69% of cases occurred among males (yellow line). There were 106,699 drug-involved overdose deaths reported in the U.S.Please note the y-axis scale varies by bar chart and caution should be applied when comparing graphs side-by-side. The bars are overlaid by lines representing gender or concurrent opioid involvement. overdose deaths involving select illicit or prescription drugs from 1999 through 2021. The figures above are bar charts showing the number of U.S.Download the data used to create these figures - Overdose_data_1999-2021 1.19.23.xlsx.Download graphs in PowerPoint - National Drug Involved Overdose Deaths 1999-2021 1.23.23 jl2.pptx.The bars are overlaid by lines showing the number of deaths involving antidepressants in combination with synthetic opioids other than methadone (primarily fentanyl) or without any opioid involvement (Source: CDC WONDER). Since then, deaths have slightly risen with 5,859 in 2021. Drug overdose deaths involving antidepressants rose steadily from 1,749 in 1999 to 5,269 in 2017. overdose deaths involving antidepressants from 1999 to 2021. The figure above is a bar and line graph showing the total number of U.S. National Drug Overdose Deaths Involving Antidepressants, by Opioid Involvement–Number Among All Ages, 1999-2021.
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